WEKA MACHINE LEARNING CLASSIFICATION IN IDENTIFYING AUTONOMIC DYSFUNCTION PARAMETERS ASSOCIATED WITH ACE INSERTION/DELETION GENOTYPES

Ethan Ng, Brett Hambly

References

  1. [1] Kahn R. Metabolic syndrome--what is the clinicalusefulness? Lancet, 371(9628),2008, 1892-3.
  2. [2] Sakkinen PA, Wahl P, Cushman M, Lewis MR,Tracy RP. Clustering of procoagulation,inflammation, and fibrinolysis variables withmetabolic factors in insulin resistance syndrome. AmJ Epidemiol, 152(10),2000, 897-907.
  3. [3] Mittal G, Gupta V, Haque SF, Khan AS. Effect ofangiotensin converting enzyme gene I/Dpolymorphism in patients with metabolic syndromein North Indian population. Chin Med J (Engl),124(1),2011, 45-8.
  4. [4] Fiatal S, Szigethy E, Szeles G, Toth R, Adany R.Insertion/deletion polymorphism of angiotensin-1converting enzyme is associated with metabolicsyndrome in Hungarian adults. J Renin AngiotensinAldosterone Syst,2011.
  5. [5] Pop-Busui R. Cardiac Autonomic Neuropathy inDiabetes. Diabetes Care, 33(2),2010, 434-41.
  6. [6] Maser RE, Mitchell BD, Vinik AI, Freeman R. Theassociation between cardiovascular autonomicneuropathy and mortality in individuals withdiabetes. Diabetes Care, 26(6),2003, 1895-901.
  7. [7] Stein PK, Reddy A. Non-linear heart rate variabilityand risk stratification in cardiovascular disease.Indian Pacing Electrophysiol J, 5(3),2005, 210-20.
  8. [8] Ziegler D. Diagnosis and treatment of diabeticautonomic neuropathy. Curr Diab Rep, 1(3),2001,216-27.
  9. [9] Thayer JF. Vagal tone and the inflammatory reflex.Cleveland Clinic Journal of Medicine, 76(Suppl2),2009, S23-S6.
  10. [10] Stein PK, Domitrovich PP, Huikuri HV, Kleiger RE.Traditional and nonlinear heart rate variability areeach independendly associated with mortality aftermyocardial infarction. J Cardiovasc Electrophysiol,16(1),2005, 13-20.
  11. [11] Khandoker AH, Jelinek HF, Palaniswami M. Heartrate variability and complexity in people withdiabetes associated cardiac autonomic neuropathy.Proc 30th IEEE EMBS Annual InternationalConference. Vancouver, Canada: IEEE Press 2008.
  12. [12] Sinnreich R, Friedlander Y, Luria MH, SapoznikovD, Kark JD. Inheritance of heart rate variability: thekibbutzim family study. Hum Genet, 105(6),1999,654-61.
  13. [13] Singh JP, Larson MG, O'Donnell CJ, Tsuji H, EvansJC, Levy D. Heritability of heart rate variability: theFramingham Heart Study. Circulation, 99(17),1999,2251-4.65
  14. [14] Busjahn A, Voss A, Knoblauch H, Knoblauch M,Jeschke E, Wessel N, et al. Angiotensin-convertingenzyme and angiotensinogen gene polymorphismsand heart rate variability in twins. Am J Cardiol,81(6),1998, 755-60.
  15. [15] Thayer JF, Merritt MM, Sollers JJ, 3rd, ZondermanAB, Evans MK, Yie S, et al. Effect of angiotensin-converting enzyme insertion/deletion polymorphismDD genotype on high-frequency heart ratevariability in African Americans. Am J Cardiol,92(12),2003, 1487-90.
  16. [16] Gayagay G, Yu B, Hambly B, Boston T, Hahn A,Celermajer DS, et al. Elite endurance athletes andthe ACE I allele--the role of genes in athleticperformance. Hum Genet, 103(1),1998, 48-50.
  17. [17] Nishikino M, Matsunaga T, Yasuda K, Adachi T,Moritani T, Tsujimoto G, et al. Genetic variation inthe renin-angiotensin system and autonomic nervoussystem function in young healthy Japanese subjects.J Clin Endocrinol Metab, 91(11),2006, 4676-81.
  18. [18] Agerholm-Larsen B, Nordestgaard BG, Tybjaerg-Hansen A. ACE gene polymorphism incardiovascular disease: meta-analyses of small andlarge studies in whites. Arterioscler Thromb VascBiol, 20(2),2000, 484-92.
  19. [19] Ljungberg L, Alehagen U, Lanne T, Bjorck H, DeBasso R, Dahlstrom U, et al. The associationbetween circulating angiotensin-converting enzymeand cardiovascular risk in the elderly: a cross-sectional study. J Renin Angiotensin AldosteroneSyst, 12(3),2011, 281-9.
  20. [20] Zintzaras E, Raman G, Kitsios G, Lau J.Angiotensin-converting enzyme insertion/deletiongene polymorphic variant as a marker of coronaryartery disease: a meta-analysis. Arch Intern Med,168(10),2008, 1077-89.
  21. [21] Sayed-Tabatabaei FA, Oostra BA, Isaacs A, vanDuijn CM, Witteman JC. ACE polymorphisms. CircRes, 98(9),2006, 1123-33.
  22. [22] Ng E, Lu, Y.X., Matthews, S., Jelinek, H.,McLachlan, C., Hambly, B. ACE I/D genotypes andtheir impact on heart rate variability: a limited meta-analysis. The 35th Annual Conference of theAustralian Society for Biophysics. Wollongong,Australia 2011.
  23. [23] Evans AE, Poirier O, Kee F, Lecerf L, McCrum E,Falconer T, et al. Polymorphisms of the angiotensin-converting-enzyme gene in subjects who die fromcoronary heart disease. Q J Med, 87(4),1994, 211-4.
  24. [24] ADInstruments. Powerlab. 1.0 ed. Australia.
  25. [25] Batchvarov V, Malik M. Measurement andinterpretation of QT dispersion. Prog CardiovascDis, 42(5),2000, 325-44.
  26. [26] Principles of care and guidelines for the managementof diabetes mellitus: NSW Department of Health;1996 November.
  27. [27] Witten H, Frank E, Data Mining: Practical MachineLearning Tools and Techniques with JavaImplementations. (Sydney: Morgan Kaufmann1989).
  28. [28] Malik M. Heart rate variability: standards ofmeasurement, physiological interpretation andclinical use. Task Force of the European Society ofCardiology and the North American Society ofPacing and Electrophysiology. Circulation,(93),1996, 1043-65.
  29. [29] Tkac I, Salagovic J, Kozarova M, Rosolova H,Molcanyiova A, Mosorjakova D, et al. Interactionbetween angiotensin-converting enzyme genotypeand glycaemic control influences lipoprotein levelsin type 2 diabetes mellitus. Wien Klin Wochenschr,115(1-2),2003, 36-40.
  30. [30] Nakhjavani M, Esfahanian F, Jahanshahi A,Esteghamati A, Nikzamir AR, Rashidi A, et al. Therelationship between the insertion/deletionpolymorphism of the ACE gene and hypertension inIranian patients with type 2 diabetes. Nephrol DialTransplant, 22(9),2007, 2549-53.
  31. [31] Provost F. Machine Learning from Imbalanced DataSets. In: N. Japkowicz, editor. Learning fromImbalanced Data Sets: Papers from the AAAIWorkshop, Austin, Texas: American Association forArtificial Intelligence, Melano Park, California;2000, 94-100.

Important Links:

Go Back