Computational Modeling of Thrombus Formation with Coupled Lattice Boltzmann and Discrete Element Methods

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Abstract

Thrombosis is a serious disease, especially when the thrombus formation occurs within any main arteries of the heart. This condition can induce to heart attack, stroke,myocardial infarction and other vital complications. The current work presents a numerical modeling of thrombus formation in a 2D vessel with the present of fatty obscure to simulate this serious disease. We used coupled Lattice Boltzmann (LBM) and Discrete Element (DEM) Method technique to model the interaction between Red Blood Cells (RBC) and blood plasma flow. The blood plasma flows simulated with Lattice Boltzmann method and red blood cells were simulated by discrete element method.

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