Gregorio Romero, Joaquin Maroto, Jose Manuel Mera, and Gillian Pearce
Biomedical engineering, Thrombectomy devices, Bond-Graph, Finite Element Analysis
In this work, we present the analysis, design and optimization of one experimental device recently developed in the UK, called the “GP” Thrombus Aspiration Device (GPTAD. This device has been designed to remove blood clots without the need to make contact with the clot itself, thereby potentially reducing the risk of problems such as downstream embolisation. To obtain the minimum pressure necessary to extract the clot and to optimize the device, we simulate the performance of the GPTAD analyzing the resistances, compliances and inertances effects. Previous full models have been undertaken using the Bond Graph technique. However in this paper we also include an analysis of the interaction between device and artery, by the introduction of Finite Elements Modeling (FEM). We model a range of diameters for the GPTAD considering a 100% occlusion case, different lengths/diameters of catheter and blood clots of various lengths. In each case we determine the optimum pressure required to extract the blood clot from the artery using the GPTAD, which is attached at its proximal end to a suction pump.
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