Surface Modification and Functionalization of Commercially Pure Titanium for Enhanced Bone Integration

Silvia Spriano and Sara Ferraris


Titanium, bone-integration, bioactivity, nanotexture


Commercially pure titanium (Ti-cp) is extensively employed for dental implants applications due to its good biocompatibility, mechanical properties and corrosion resistance. The present research work considers an innovative surface treatment, in order to improve the bone bonding ability of Ti-cp implants. The process include two phases: inorganic modification, aimed to obtain a thicker titanium oxide layer with a bioactive behaviour, micro and nano-textures and a high hydroxylazion degree, and functionalization with biomolecules able to promote osteointegration (alkaline phosphatase), in order to confer a more specific biological bioactivity.

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