EFFECTS OF CHANGES OF ISCHAEMIC REGION CONDUCTIVITY IN THE HEART: A 1D MODEL

Peter R. Johnston

Keywords

Bidomain model, Cardiac ischaemia, Conductiv-ity changes, One-dimensional model, Finite volumemethod.

Abstract

The effects of changes in cardiac tissue conductivity within a region of cardiac ischaemia are studied via a simple one dimensional model of the tissue. The one dimensional bidomain equation governing the electric potential within the heart is solved analytically using simple assumptions regarding the variation in conduc- tivity within the tissue. This simple model indicates that a greater reduction in intracellular conductivity than in extracellular conductivity leads to an increase in heart surface potentials and vice-versa. It is also demonstrated that this result is in accord with obser- vations from the numerical solution of the full three dimensional bidomain equation.

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