X. Deng and Y. Fan (PRC)
Flow disturbance, arterial stenosis, atherosclerosis, wall shear stress
Using a sudden tubular expansion as a model of an arterial stenosis, the effect of disturbed flow on mass transfer from the arterial wall to flowing blood was studied theoretically and tested experimentally by measuring the dissolution rate of benzoic acid pellets forming the outer tube of a sudden tubular expansion. The study revealed that mass transfer from vessel wall to flowing fluid in regions of disturbed flow is independent of wall shear rates. The results imply that flow disturbance may enhance the transport of biochemicals synthesized within the blood vessel wall but may not affect the transport of macromolecules such as plasma proteins and lipoproteins from the blood vessel wall to flowing blood.
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