Computer Simulation of Cardiomyocyte Ion Channels System and Excitation-Contraction Coupling

M. Fischer and S. Konvickova (Czech Republic)


Ion channels, excitation-contraction coupling, cardiomyocyte, computer simulation.


The computational model of ion channels and ion transportation in cardiomyocyte is presented in this paper. The validity of the model is discussed and the results are compared to physiological experimental findings. Although only calcium ions are involved in this moment, the model gives results well consistent with experimental data. Thus this simulation can be useful for studying ion channel attributes and their impact on sarcomere function.

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