T. Hope, P. Gregson, N. Linney, and M. Schmidt (Canada)
ultrasound tissue characterization, white matter damage,ultrasound image texture
Premature infants are prone to white matter damage
(WMD), which is associated with cerebral palsy (CP) and
cognitive impairment. Ultrasound (US) is the preferred
imaging modality to detect WMD. To improve on existing
diagnostic rates, quantitative measures incorporating new
information are needed. We are investigating US texture
measures as new indicators of white matter health. We are
developing techniques which enhance image texture differ
ences that may reflect pathological changes.
Earlier experiments using data from 30 patients indicate
that tissue types may be segmented based on texture mea
sures. Present experiments using images from 18 patients
(12 with normal outcome, 6 who developed CP) reveal that
the measures from CP patients form separate populations
from healthy patients. Texture measures were obtained
without compensating for operator-dependent machine set
tings and without suppressing speckle. Digitized analogue
ultrasound films are used as the input data since modern
digital ultrasound machines have bandwidth restrictions.
The effect of image resolution reduction on the texture
based methods is part of an on-going investigation.